BookAmy R. Borenstein, Ph.D, M.P.H., and James A. Mortimer, Ph.D., and James Mortimer, University of South Florida, Department of Epidemiology and Biostatistics, Department of Neurology, Tampa, FL, USA.
Contents:
The "first" case
Clinical appearance, progression, and classification
Epidemiologic definition of a case
Neuropathology of Alzheimer's disease
The threshold model of dementia
The prevalence of Alzheimer's disease
The incidence of Alzheimer's disease
Survival and mortality in Alzheimer's disease
Introduction to the analytic epidemiology of Alzheimer's disease
Family history, genetics, and down syndrome
Early-life factors
Traumatic brain injury
Cigarette smoking and alcohol consumption
Vascular disease
Diet
Physical activity
Cognitive activity
Social engagement
Nonsteroidal anti-inflammatory drugs, hormone replacement therapy, and anticholinergic medications
Prodromal markers of disease or causal risk factors? Depression, olfaction, and subjective memory complaints
Fluid, imaging, and cognitive biomarkers
Risk assessment and prevention of Alzheimer's disease
Summary and recommendations.